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A new drug approved for weight-loss from the U.S. Food and Drug Administration had achievement in clinical trials, but it isn’t a panacea for weight reduction. It must be employed in combination with a low-calorie diet and routine workouts in order to be effective.
Using two separate drugs to shed weight can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you should err on the side of caution and allow FDA do its job and demand some investigation be done so your public understands the side effects and hazards of the medications before we bring them. Keep in mind that drug companies are in business to earn money and that they would say almost anything to keep people on their own medications.
Researchers found that participants taking this drug for any year, dropped a few pounds within 4 weeks and have kept the load off through the entire 56 weeks of the study. Contrave is a combination with the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which are made up of several active ingredient, which can make them more potent and safer.
Combo-pilling is the newest fad or also the newest to come under scrutiny and therefore it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular could be the fact that at the time of right now there are not any long term prescription weightloss pills that have been authorized by the FDA other than orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be authorized by the FDA.
Seizures really are a side effect with Contrave and shouldn’t be taken in those with seizure disorders. The drug also can raise blood pressure levels and heart rate, and really should not be used in those with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug.
The FDA also warned that Contrave can raise blood pressure and heartbeat and must stop used in patients with uncontrolled high hypertension, along with by a person with heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients which has a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients for the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking.
“There were no signs and symptoms of depression or suicidal thoughts in trial participants,” said Fujioka.